Healing & Tissue Repair Peptides
Explore healing & repair profiles and evidence guides by mechanism, research stage, safety context, and primary sources.
Research area
How to use this hub
Category membership organizes related research questions. It does not establish effectiveness, approval, or suitability for a person.
Evidence boundary
Repair claims often begin in cell or animal injury models. Check the exact molecule, route, model, and availability of controlled human outcomes before translating a result.
Start here
Build context before interpreting an individual profile.
Healing peptide evidence map
Compare repair claims by molecule, model, route, and human-evidence boundary.
Read guideBPC-157 research guide
Audit the evidence, trial record, safety limits, and regulatory context.
Read guideTB-500 research guide
Separate TB-500 claims from thymosin beta-4 research and human evidence.
Read guideProfiles in this research area
Open a profile for its mechanism, evidence stage, safety context, and linked references.
BPC-157BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from human gastric juice that promotes wound healing, angiogenesis, and…TB-500TB-500 is a synthetic fragment of thymosin beta-4, a 43-amino acid protein involved in actin regulation, tissue repair, wound healing, and anti-inflam…GHK-CuGHK-Cu is a naturally occurring copper-binding tripeptide that modulates gene expression, attenuates inflammation, improves antioxidant responses, and…KPVKPV is a C-terminal tripeptide fragment of alpha-melanocyte stimulating hormone with potent anti-inflammatory properties. It is primarily researched f…Ara 290ARA-290 (cibinetide) is a synthetic 11-amino acid peptide derived from the non-hematopoietic tissue-protective region of erythropoietin that selective…AbaloparatideAbaloparatide is a synthetic 34-amino acid analog of parathyroid hormone-related protein (PTHrP 1-34), FDA-approved in 2017 for postmenopausal osteopo…Adipotide (FTPP)Adipotide (FTPP) is an experimental peptidomimetic that induces targeted apoptosis in blood vessels supplying white adipose tissue, with research appl…AHK (Tripeptide-3)AHK (Tripeptide-3) is a three-amino-acid peptide (Ala-His-Lys) investigated for its effects on hair growth, wound healing, and skin rejuvenation. It a…AHK-CuAHK-Cu is a copper-complexed tripeptide (Ala-His-Lys-Cu) studied for its effects on collagen synthesis, hair growth, and wound healing. It modulates V…ANA Gold (Gold Tripeptide-1)ANA Gold is a colloidal gold-tripeptide-1 conjugate that combines gold nanoparticle anti-inflammatory and antioxidant properties with tripeptide-1's c…ApraglutideA next-generation, long-acting glucagon-like peptide-2 (GLP-2) analog engineered for once-weekly dosing in short bowel syndrome.BecaplerminRecombinant human platelet-derived growth factor-BB in a topical gel; the first and only pharmacological agent FDA-approved to treat a chronic wound (…BPC-157 / TB-500 BlendA research peptide blend combining BPC-157 (Body Protection Compound) and TB-500 (Thymosin Beta-4 fragment), two tissue-repair peptides with complemen…CardiogenCardiogen (AEDR) is a synthetic tetrapeptide bioregulator that modulates fibroblast activity in cardiac tissue, studied for its cardioprotective effec…CartalaxCartalax (AED) is a synthetic tripeptide bioregulator that modulates fibroblast function across multiple tissues, studied for its geroprotective effec…CJC-1295 / GHRP-6 BlendA research peptide blend combining CJC-1295 (no DAC), a GHRH analogue, with GHRP-6, a synthetic ghrelin analogue, to synergistically elevate growth ho…EGF (Epidermal Growth Factor)EGF is a 53-amino acid polypeptide that binds the EGF receptor to stimulate cell proliferation, differentiation, and survival, with applications in wo…Glow Blend (TB-500 / BPC-157 / GHK-Cu)A research peptide blend combining TB-500 (10mg), BPC-157 (10mg), and GHK-Cu (50mg) — three tissue-repair and anti-aging peptides with complementary m…
Show 33 more profiles
Glow ProtocolGlow Protocol is a multi-compound regimen combining skin-supporting peptides, antioxidants, and growth factors designed to enhance dermal collagen syn…GLOW ProtocolA combination protocol pairing BPC-157, TB-500 (thymosin beta-4 fragment) and the copper peptide GHK-Cu, marketed for skin, hair and connective-tissue…GLP-2 (Glucagon-Like Peptide-2)GLP-2 is a 33-amino acid intestinotrophic peptide hormone derived from proglucagon processing in intestinal L-cells. It promotes intestinal mucosal gr…HGHHuman growth hormone, a 191-amino acid peptide hormone produced by the pituitary gland that regulates growth, body composition, metabolism, and cellul…Histatin 5Histatin 5 is a 24-amino acid histidine-rich salivary antimicrobial peptide with potent antifungal activity against Candida albicans, acting through a…IGF-1 LR3IGF-1 LR3 is a synthetic modified construct of insulin-like growth factor-1 with an extended half-life that enhances cell division, fat metabolism, an…Intestinal Trefoil Factor (ITF/TFF3)Intestinal Trefoil Factor (TFF3) is a 59-amino acid trefoil peptide secreted by goblet cells that plays a central role in mucosal restitution and epit…IpamorelinIpamorelin is a highly selective growth hormone secretagogue pentapeptide that binds the ghrelin receptor without affecting ACTH, prolactin, or cortis…KGF (Keratinocyte Growth Factor)KGF (FGF-7) is a 163-amino acid growth factor that specifically targets keratinocytes via the FGFR2-IIIb receptor, with clinical applications in mucos…KLOW ProtocolThe GLOW stack (BPC-157 + TB-500 + GHK-Cu) plus the anti-inflammatory tripeptide KPV -- a four-peptide blend aimed at tissue repair with an added anti…Klow80 Blend (TB-500 / BPC-157 / GHK-Cu / KPV)An 80mg research peptide blend combining TB-500 (10mg), BPC-157 (10mg), GHK-Cu (50mg), and KPV (10mg) — integrating potent anti-inflammatory action wi…LIRAGLUTIDELiraglutide is a long-acting GLP-1 receptor agonist studied for its effects on glucose homeostasis, appetite regulation, cardiovascular protection, an…LivagenLivagen is a short bioregulatory tetrapeptide that decondenses chromatin to reactivate silenced genes, with research applications in immune system rej…LL-37LL-37 is the only human cathelicidin antimicrobial peptide, playing a critical role in innate immunity through direct antimicrobial activity, immunomo…MatrixylMatrixyl (palmitoyl pentapeptide-4) is a synthetic lipopeptide that stimulates collagen, collagen IV, and hyaluronic acid synthesis in skin fibroblast…MGFMechano Growth Factor, a splice variant of IGF-1 produced in response to mechanical stress, that activates muscle satellite cells and promotes localiz…MotilinMotilin is a 22-amino-acid peptide hormone produced by Mo cells of the duodenal and jejunal mucosa that regulates interdigestive gastrointestinal moti…OvagenOvagen (Thr-Glu-Asp-Phe) is a synthetic tetrapeptide bioregulator targeting hepatic and gastrointestinal tissue, researched for hepatoprotective effec…OxytocinOxytocin is a 9-amino acid endogenous neuropeptide produced in the hypothalamus that regulates social bonding, stress response, wound healing, and inf…PEG-MGFPEG-MGF (PEGylated Mechano-Growth Factor) is a modified form of IGF-1 that stimulates myoblast proliferation and differentiation, with research applic…Pexiganan (MSI-78)22-amino-acid synthetic analog of the frog-skin peptide magainin 2, developed as a topical antimicrobial for infected diabetic foot ulcers.SemaglutideSemaglutide is a GLP-1 receptor agonist that mimics the incretin hormone GLP-1 to regulate blood sugar, reduce appetite, and promote weight loss. It i…StamakortStamakort is a complex peptide bioregulator preparation derived from gastric mucosal tissue, developed for targeted support of stomach function and ga…Super Human Blend (CJC-1295 + Ipamorelin + BPC-157 + TB-500)The Super Human Blend is a compounded four-peptide combination of CJC-1295 (GHRH analog), Ipamorelin (GH secretagogue), BPC-157 (tissue repair peptide…TB-500 (Ac-LKKTETQ)A synthetic fragment of Thymosin Beta-4 containing the active acetylated LKKTETQ sequence that promotes tissue repair by regulating actin-based cell m…TeduglutideA DPP-4-resistant glucagon-like peptide-2 (GLP-2) analog that promotes intestinal mucosal growth and absorption in short bowel syndrome.TeriparatideA recombinant form of the first 34 amino acids of human parathyroid hormone (PTH 1-34) used to treat severe osteoporosis by stimulating osteoblast act…Thymosin Beta-4A 43-amino acid peptide that is the major actin-sequestering molecule in mammalian cells, playing critical roles in tissue repair, wound healing, angi…Tri-Heal Max ProtocolAn enhanced healing peptide protocol combining TB-500, BPC-157, and KPV to accelerate tissue recovery by leveraging synergistic mechanisms of cellular…Tripeptide-29Tripeptide-29 is a collagen-fragment tripeptide and GHK analogue that stimulates procollagen I synthesis and promotes wound healing by mimicking a typ…VesugenVesugen is a synthetic tripeptide bioregulator (Lys-Glu-Asp) that modulates gene expression and protein synthesis, particularly through SIRT1 upregula…VIPVasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide with potent anti-inflammatory, immunomodulatory, and neuroprotective properties, w…Wolverine StackThe Wolverine Stack combines BPC-157, a synthetic gastric peptide promoting angiogenesis and tissue repair, with TB-500 (thymosin beta-4 fragment), wh…
Read the full category research notes
These notes map terminology and research themes. Verify claims in the linked profile references and current primary records.
Healing & Tissue Repair Peptides
This category covers peptides studied for their ability to accelerate wound healing, promote angiogenesis (new blood vessel formation), enhance cell migration, and support tissue regeneration. These peptides act through diverse mechanisms including growth factor modulation, nitric oxide signaling, and extracellular matrix remodeling.
Complete Peptide Directory
| Peptide | Description | Primary Mechanism |
|---|---|---|
| BPC-157 | Gastric pentadecapeptide with broad tissue-protective and healing properties | Promotes angiogenesis via VEGF, NO system modulation, cytoprotective signaling |
| BPC-157 Arginate | Arginine salt form of BPC-157 with enhanced stability | Same mechanism as BPC-157 with improved formulation characteristics |
| BPC-157 Nasal | Intranasal formulation of BPC-157 for CNS-targeted delivery | BPC-157 mechanisms with enhanced blood-brain barrier penetration |
| BPC-157 Stable | Stabilized form of BPC-157 resistant to degradation | Enhanced stability BPC-157 for oral and systemic applications |
| BPC-157 / TB-500 Blend | Combination of two complementary tissue-repair peptides | Synergistic angiogenesis (BPC-157) and cell migration (TB-500) |
| TB-500 | Synthetic thymosin beta-4 fragment for tissue repair and recovery | Regulates actin polymerization, promotes cell migration and wound closure |
| TB-4 Frag | N-terminal fragment (Ac-SDKP) of thymosin beta-4 | Anti-fibrotic and anti-inflammatory activity in cardiovascular and renal tissue |
| GHK-Cu | Copper tripeptide that modulates thousands of genes for tissue remodeling | Stimulates collagen, elastin, and glycosaminoglycan synthesis; anti-inflammatory |
| KPV | Alpha-MSH C-terminal tripeptide with potent anti-inflammatory activity | Inhibits NF-kB and pro-inflammatory cytokines; repairs intestinal barrier |
| AHK-Cu | Copper tripeptide for collagen synthesis and wound healing | VEGF and TGF-beta1 modulation; fibroblast activation |
| AHK (Tripeptide-3) | Fibroblast-activating peptide for tissue regeneration | Stimulates fibroblast proliferation and extracellular matrix production |
| PEG-MGF | PEGylated mechano-growth factor for muscle and bone repair | Activates satellite cells; promotes muscle regeneration and bone healing |
| Mechano Growth Factor | IGF-1 splice variant produced in response to mechanical stress | Muscle repair, satellite cell activation, exercise recovery |
| Follistatin-315 | Myostatin-binding protein that promotes muscle growth and recovery | Binds and neutralizes myostatin; enhances muscle regeneration |
| Collagen Tripeptide | Bioactive tripeptide fragment from collagen hydrolysis | Stimulates fibroblast collagen production; supports skin and joint repair |
| Collost | Collagen-based biomaterial for wound healing applications | Provides extracellular matrix scaffold for tissue regeneration |
| Gut Inflammation BPC-157 Formula | Multi-compound gut-healing formulation built around BPC-157 | Combined gut barrier repair through multiple complementary mechanisms |
| Gut Inflammation BPC-157 Arginate Formula | Arginate-based gut-healing formulation with enhanced stability | BPC-157 arginate-centered approach to intestinal inflammation |
| Osteopontin Peptide | Peptide derived from osteopontin, a key bone matrix protein | Bone remodeling, mineralization, and immune-skeletal signaling |
| BMP-2 | Bone morphogenetic protein-2 for skeletal tissue engineering | Induces osteoblast differentiation and bone formation |
| BMP-7 | Bone morphogenetic protein-7 for bone and kidney repair | Promotes bone healing and has renal protective properties |
Common Research Themes
Angiogenesis: BPC-157 and TB-500 both promote new blood vessel formation, but through distinct pathways — BPC-157 via the NO system and VEGF, TB-500 via actin regulation and endothelial cell migration.
Extracellular Matrix Remodeling: GHK-Cu, AHK-Cu, and Collagen Tripeptide stimulate fibroblast activity and collagen/elastin production, making them relevant to both wound healing and anti-aging skin research.
Gut Barrier Repair: BPC-157 and KPV both target intestinal inflammation through complementary mechanisms — BPC-157 through cytoprotective signaling, KPV through direct NF-kB inhibition.
Bone & Skeletal Repair: BMP-2, BMP-7, and Osteopontin Peptide address skeletal tissue regeneration through growth factor signaling and osteoblast activation.
Getting Started
If you are new to this category, we recommend starting with BPC-157 — the most extensively studied healing peptide with over 100 preclinical studies across multiple tissue types. From there, explore related peptides through the See Also sections on each page to build a comprehensive understanding of the research landscape.