Muscle & Performance Peptides

Explore muscle & performance profiles and evidence guides by mechanism, research stage, safety context, and primary sources.

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Category membership organizes related research questions. It does not establish effectiveness, approval, or suitability for a person.

Evidence boundary

Muscle signaling, hormone concentrations, body composition, rehabilitation, and athletic performance are different outcomes with different safety and rule contexts.

Profiles

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Research methodology

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What is IGF-1?

Understand the growth-factor axis, laboratory measures, and evidence limits.

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Peptides vs SARMs

Compare compound classes, mechanisms, evidence, and major safety differences.

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Sermorelin vs HGH

Compare stimulation, replacement, exposure, evidence, and regulatory context.

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Profiles in this research area

Open a profile for its mechanism, evidence stage, safety context, and linked references.

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IGF-1 LR3IGF-1 LR3 is a synthetic modified construct of insulin-like growth factor-1 with an extended half-life that enhances cell division, fat metabolism, an…MGFMechano Growth Factor, a splice variant of IGF-1 produced in response to mechanical stress, that activates muscle satellite cells and promotes localiz…PEG-MGFPEG-MGF (PEGylated Mechano-Growth Factor) is a modified form of IGF-1 that stimulates myoblast proliferation and differentiation, with research applic…Follistatin 344Follistatin 344 is a naturally occurring glycoprotein that binds and neutralizes activin and myostatin, potent inhibitors of muscle growth, making it …AC-262536AC-262536 is a non-steroidal selective androgen receptor modulator (SARM) with high binding affinity (Ki = 5 nM) that demonstrates tissue-selective an…BMS-564929BMS-564929 is a potent, orally bioavailable nonsteroidal selective androgen receptor modulator (SARM) developed by Bristol-Myers Squibb for the potent…CJC-1295 (without DAC)CJC-1295 without DAC (Modified GRF 1-29) is a synthetic analog of growth hormone-releasing hormone with four amino acid substitutions that enhance met…CJC-1295 / GHRP-2 BlendA research peptide blend combining CJC-1295 (no DAC) and GHRP-2, two growth hormone secretagogues that act on distinct receptor pathways (GHRH-R and G…CJC-1295 / GHRP-6 BlendA research peptide blend combining CJC-1295 (no DAC), a GHRH analogue, with GHRP-6, a synthetic ghrelin analogue, to synergistically elevate growth ho…EGF (Epidermal Growth Factor)EGF is a 53-amino acid polypeptide that binds the EGF receptor to stimulate cell proliferation, differentiation, and survival, with applications in wo…Follistatin-315Follistatin-315 is a naturally occurring activin- and myostatin-binding glycoprotein isoform studied for its roles in muscle growth, inflammation regu…GDF-11GDF-11 (Growth Differentiation Factor 11) is a member of the TGF-beta superfamily that gained prominence from parabiosis rejuvenation studies, with de…GHRH (Growth Hormone Releasing Hormone)GHRH is a 44-amino acid endogenous hypothalamic peptide that stimulates pulsatile growth hormone release from the anterior pituitary. It is the primar…GHRP-6GHRP-6 is a synthetic ghrelin receptor agonist and growth hormone secretagogue with research applications in neuroprotection, memory, wound healing, c…GLPG-0492A non-steroidal selective androgen receptor modulator (SARM) developed by Galapagos NV for the treatment of muscle-wasting conditions.GSK-2849466An investigational non-steroidal selective androgen receptor modulator (SARM) developed by GlaxoSmithKline for muscle-wasting and androgen deficiency …GSK-2881078A non-steroidal SARM from GlaxoSmithKline that advanced to Phase II clinical trials targeting muscle mass improvement in older adults and chronic dise…GSK-971086An early-stage non-steroidal SARM from GlaxoSmithKline investigated for androgen receptor-mediated anabolic effects on muscle and bone.

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GTX-027A next-generation SARM developed by GTx Inc. as an optimized follow-up to Ostarine (GTX-024) with improved anabolic potency and selectivity.GW0742A highly selective PPARδ agonist structurally related to Cardarine (GW501516), investigated for metabolic regulation, endurance enhancement, and anti-…IGF-1IGF-1 is an endogenous 70-amino acid polypeptide structurally similar to insulin that mediates most of growth hormone's anabolic effects. It plays cri…IGF-1 DESDes(1-3) IGF-1 is a truncated form of insulin-like growth factor-1 missing the first three amino acids, resulting in dramatically reduced IGFBP bindin…IGF-2IGF-2 (Insulin-like Growth Factor 2) is a 67 amino acid peptide hormone critical for fetal growth and development, regulated by genomic imprinting. It…IPA Blend (CJC-1295 / Ipamorelin)A research peptide blend combining CJC-1295 (Mod GRF 1-29, 5mg) with Ipamorelin (10mg), pairing a GHRH analogue with a selective ghrelin receptor agon…KGF (Keratinocyte Growth Factor)KGF (FGF-7) is a 163-amino acid growth factor that specifically targets keratinocytes via the FGFR2-IIIb receptor, with clinical applications in mucos…Mod GRF / Ipamorelin / GHRP-2 BlendA triple-peptide research blend combining Mod GRF 1-29 (a modified GHRH analogue), Ipamorelin, and GHRP-2 (both ghrelin receptor agonists), designed t…SermorelinSermorelin is a synthetic 29-amino acid analogue of growth hormone-releasing hormone (GHRH) used to assess and stimulate natural growth hormone secret…Sermorelin / GHRP-6 / GHRP-2 BlendA triple-peptide research blend combining Sermorelin (a GHRH analogue) with GHRP-6 and GHRP-2 (both ghrelin receptor agonists), studied for synergisti…Somatropin (rHGH)Somatropin is recombinant human growth hormone (rHGH), a 191-amino acid protein identical to endogenous pituitary-derived growth hormone. It is FDA-ap…Super Human Blend (CJC-1295 + Ipamorelin + BPC-157 + TB-500)The Super Human Blend is a compounded four-peptide combination of CJC-1295 (GHRH analog), Ipamorelin (GH secretagogue), BPC-157 (tissue repair peptide…Super Shred (AOD-9604 + CJC-1295 + Ipamorelin)The Super Shred blend is a compounded three-peptide fat loss stack combining AOD-9604 (anti-obesity GH fragment), CJC-1295 (GHRH analog), and Ipamorel…TB-500TB-500 is a synthetic fragment of thymosin beta-4, a 43-amino acid protein involved in actin regulation, tissue repair, wound healing, and anti-inflam…TRT (Testosterone Replacement Therapy)A clinical therapy guide covering testosterone replacement in men with diagnosed hypogonadism -- indications, formulations, benefits, risks and monito…

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These notes map terminology and research themes. Verify claims in the linked profile references and current primary records.